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KMID : 1003820180220010011
Journal Of The Korea Institute Of Oriental Medical Diagnostics
2018 Volume.22 No. 1 p.11 ~ p.18
Analysis of Papers on Curcuma longa Rhizoma for Possibility Evaluation of Therapeutic against dementia
Jo Na-Young

Abstract
Objectives: The incidence of degenerative diseases is increasing as society ages, and this increased the economic burden on society. Oxidative stress was also under suspicion as one of the causes. Recent studies have found that Curcuma longa Rhizoma had antioxidant, anti-inflammatory, antimutagenic, and anticancer effects. Through this study, we figure out trends in Curcuma longa Rhizoma research and evaluate the therapeutic potential of Curcuma longa Rhizoma for dementia.

Methods: The search was made using domestic and international internet search sites. ¡°Naver academic,¡± ¡°Google scholar,¡± ¡°Korea institute of oriental medicine (KIOM OASIS),¡± ¡°Korean traditional knowledge portal (KTKP),¡± ¡°Library of Congress,¡± ¡°Research information sharing service (RISS),¡± ¡°National Digital Science Links (NDSL),¡± and ¡°Pub med¡± are used to search. The searched for words were ¡°turmeric,¡± ¡°Curcuma longa Rhizoma,¡± ¡°antioxidant,¡± and ¡°nerve regeneration.¡±

Results: It could be seen that a lot of research done on Curcuma longa recently. In previous studies, the most common research disease was cancer. In previous studies, the most common effects of Curcuma longa was antioxidant and anticancer. Curcumin, Vitamin B1, and various essential oils were the functional components of Curcuma longa Rhizoma. Curcuma longa Rhizoma performs DPPH radical scavenging activity and ABTS radical cation decolorization activity; it inhibits NO and iNOS.

Conclusion: The destruction of nerve cells due to oxidative stress is a cause of dementia. Curcuma longa Rhizoma have antioxidant effects. Therefore, we believed that it is an effective treatment for dementia. Various studies will be made on Curcuma longa Rhizoma.
KEYWORD
Curcuma longa, Rhizoma dementia, antioxidant, Korean medicine
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